2021 updates in postoperative radiotherapy section of Chinese Society of Clinical Oncology Breast Cancer guideline

: As an integral part of the Chinese Society Clinical Oncology Breast Cancer (CSCO BC) guideline, radiation therapy (RT) section was issued in 2017 and updated annually. The panel members make risk-adapted stratified practical clinical recommendations postoperative RT which reflect latest global literature field high-quality trials from academic centers a timely manner. Considering another function encouraging physicians to participate trials, footnotes highlight controversies that existed decision making, importance modern techniques decreasing toxicity, main evidence supporting treatment each scenario, including “grey zones”. 2021 CSCO BC guideline can be summarized as follows: (I) prioritize routine practice hypofractionated regime RT, especially breast-conserving patients receiving whole-breast irradiation without regional nodal (RNI). Apart 3-week based moderated whole breast (WBI), one week schedule is also included recommendation for selective node negative patients. (II) Refine decision-making T1-2 N1 omitting low risk conservative surgery; (III) recommend comprehensive criteria technical details. hope evidence-based continuously contribute improved standardization radiotherapy synchronizing following results research.